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Transient excited states of the metamorphic protein Mad2 and their implications for function
The spindle checkpoint complex is a key surveillance mechanism in cell division that prevents premature separation of sister chromatids. Mad2 is an integral component of this spindle checkpoint complex that recognizes cognate substrates such as Mad1 and Cdc20 in its closed (C-Mad2) conformation by f...
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| Udgivet i: | Proteins |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2025
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616478/ https://ncbi.nlm.nih.gov/pubmed/38221646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.26667 |
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