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Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy
How proteins switch between various ligand-free and ligand-bound structures has been a key biophysical question ever since the postulation of the Monod-Wyman-Changeux and Koshland-Nemethy-Filmer models over six decades ago. The ability of NMR spectroscopy to provide structural and kinetic informatio...
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| Udgivet i: | J Magn Reson Open |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2022
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612731/ https://ncbi.nlm.nih.gov/pubmed/35586549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmro.2022.100034 |
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