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Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

How proteins switch between various ligand-free and ligand-bound structures has been a key biophysical question ever since the postulation of the Monod-Wyman-Changeux and Koshland-Nemethy-Filmer models over six decades ago. The ability of NMR spectroscopy to provide structural and kinetic informatio...

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Detalhes bibliográficos
Publicado no:J Magn Reson Open
Main Authors: Jain, Shefali, Sekhar, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612731/
https://ncbi.nlm.nih.gov/pubmed/35586549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmro.2022.100034
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