Prenatal efavirenz exposure is independently associated with maternal, but not fetal CYP2B6 genotype

OBJECTIVES: Understanding the influence of fetal and maternal genetics on prenatal drug exposure could potentially improve benefit-risk evaluation. In this study, we investigated the impact of two functional polymorphisms in CYP2B6 on prenatal exposure to efavirenz. METHODS: Dried blood spot (DBS) s...

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Veröffentlicht in:Pharmacogenet Genomics
Hauptverfasser: Eniayewu, Oluwasegun, Akinloye, Abdulafeez, Shenkoya, Babajide, Azuka, Uche, Bolaji, Oluseye, Adejuyigbe, Ebunoluwa, Owen, Andrew, Olagunju, Adeniyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2024
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616417/
https://ncbi.nlm.nih.gov/pubmed/38934229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000542
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