Breast milk pharmacokinetics of efavirenz and breastfed infants’ exposure in genetically-defined subgroups of mother-infant pairs: an observational study

BACKGROUND: The antiretroviral drug efavirenz is widely used during breastfeeding. Evaluating its safety requires an understanding of its breast milk pharmacokinetics, level of breastfed infants’ exposure and potential influence of polymorphisms in drug disposition genes. METHODS: For this observati...

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Vydáno v:Clin Infect Dis
Hlavní autoři: Olagunju, Adeniyi, Bolaji, Oluseye, Amara, Alieu, Waitt, Catriona, Else, Laura, Adejuyigbe, Ebunoluwa, Siccardi, Marco, Back, David, Khoo, Saye, Owen, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542686/
https://ncbi.nlm.nih.gov/pubmed/25882300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ317
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