Breast milk pharmacokinetics of efavirenz and breastfed infants’ exposure in genetically-defined subgroups of mother-infant pairs: an observational study

BACKGROUND: The antiretroviral drug efavirenz is widely used during breastfeeding. Evaluating its safety requires an understanding of its breast milk pharmacokinetics, level of breastfed infants’ exposure and potential influence of polymorphisms in drug disposition genes. METHODS: For this observati...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Olagunju, Adeniyi, Bolaji, Oluseye, Amara, Alieu, Waitt, Catriona, Else, Laura, Adejuyigbe, Ebunoluwa, Siccardi, Marco, Back, David, Khoo, Saye, Owen, Andrew
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542686/
https://ncbi.nlm.nih.gov/pubmed/25882300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ317
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