MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis

Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors and responds to such changes remains unclear. Here, we describe a protective mechanism by which mucosal-associated invariant T (MAIT) cells detect microbiota metabolites produced upon intestinal inflammation...

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Pubblicato in:Sci Immunol
Autori principali: El Morr, Yara, Fürstenheim, Mariela, Mestdagh, Martin, Franciszkiewicz, Katarzyna, Salou, Marion, Morvan, Claire, Dupré, Thierry, Vorobev, Alexey, Jneid, Bakhos, Premel, Virginie, Darbois, Aurélie, Perrin, Laetitia, Mondot, Stanislas, Colombeau, Ludovic, Bugaut, Hélène, du Halgouet, Anastasia, Richon, Sophie, Procopio, Emanuele, Maurin, Mathieu, Philippe, Catherine, Rodriguez, Raphael, Lantz, Olivier, Legoux, François
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2024
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616241/
https://ncbi.nlm.nih.gov/pubmed/38905325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.adi8954
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