MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis

Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors and responds to such changes remains unclear. Here, we describe a protective mechanism by which mucosal-associated invariant T (MAIT) cells detect microbiota metabolites produced upon intestinal inflammation...

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Gepubliceerd in:Sci Immunol
Hoofdauteurs: El Morr, Yara, Fürstenheim, Mariela, Mestdagh, Martin, Franciszkiewicz, Katarzyna, Salou, Marion, Morvan, Claire, Dupré, Thierry, Vorobev, Alexey, Jneid, Bakhos, Premel, Virginie, Darbois, Aurélie, Perrin, Laetitia, Mondot, Stanislas, Colombeau, Ludovic, Bugaut, Hélène, du Halgouet, Anastasia, Richon, Sophie, Procopio, Emanuele, Maurin, Mathieu, Philippe, Catherine, Rodriguez, Raphael, Lantz, Olivier, Legoux, François
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2024
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616241/
https://ncbi.nlm.nih.gov/pubmed/38905325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.adi8954
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