MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis

Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors and responds to such changes remains unclear. Here, we describe a protective mechanism by which mucosal-associated invariant T (MAIT) cells detect microbiota metabolites produced upon intestinal inflammation...

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Publié dans:Sci Immunol
Auteurs principaux: El Morr, Yara, Fürstenheim, Mariela, Mestdagh, Martin, Franciszkiewicz, Katarzyna, Salou, Marion, Morvan, Claire, Dupré, Thierry, Vorobev, Alexey, Jneid, Bakhos, Premel, Virginie, Darbois, Aurélie, Perrin, Laetitia, Mondot, Stanislas, Colombeau, Ludovic, Bugaut, Hélène, du Halgouet, Anastasia, Richon, Sophie, Procopio, Emanuele, Maurin, Mathieu, Philippe, Catherine, Rodriguez, Raphael, Lantz, Olivier, Legoux, François
Format: Artigo
Langue:Inglês
Publié: 2024
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616241/
https://ncbi.nlm.nih.gov/pubmed/38905325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.adi8954
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