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Germinal Center vs Extrafollicular Responses in Systemic Autoimmunity: Who Turns the Blade on Self?

Spontaneously formed germinal centers (GCs) have been reported in most mouse models of human autoimmune disease and autoimmune patients, and have long been considered a source of somatically-mutated and thus high affinity autoantibodies, but their role in autoimmunity is becoming increasingly contro...

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Библиографические подробности
Опубликовано в: :Adv Immunol
Главные авторы: He, Yuke, Vinuesa, Carola G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2024
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616122/
https://ncbi.nlm.nih.gov/pubmed/38866437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ai.2024.02.002
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