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Structural basis of human U5 snRNP late biogenesis and recycling

Pre-mRNA splicing by the spliceosome requires the biogenesis and recycling of its small nuclear ribonucleoprotein complexes (snRNPs), which are consumed in each round of splicing. The human U5 snRNP is the ~1 megadalton “heart” of the spliceosome and is recycled through an unknown mechanism involvin...

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Detalles Bibliográficos
Publicado en:Nat Struct Mol Biol
Autores principales: Bassat, Daria Riabov, Visanpattanasin, Supapat, Vorländer, Matthias K., Fin, Laura, Phillips, Alexander W., Plaschka, Clemens
Formato: Artigo
Lenguaje:Inglês
Publicado: 2024
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616108/
https://ncbi.nlm.nih.gov/pubmed/38467876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-024-01243-4
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