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MLL regulates the actin cytoskeleton and cell migration by stabilising Rho GTPases via the expression of RhoGDI1

Attainment of proper cell shape and the regulation of cell migration are essential processes in the development of an organism. The mixed lineage leukemia (MLL or KMT2A) protein, a histone 3 lysine 4 (H3K4) methyltransferase, plays a critical role in cell-fate decisions during skeletal development a...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Chinchole, Akash, Lone, Kaisar Ahmad, Tyagi, Shweta
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615853/
https://ncbi.nlm.nih.gov/pubmed/36111497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.260042
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