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Reconsidering pluripotency tests: Do we still need teratoma assays?

The induction of teratoma in mice by the transplantation of stem cells into extra-uterine sites has been used as a read-out for cellular pluripotency since the initial description of this phenomenon in 1954. Since then, the teratoma assay has remained the assay of choice to demonstrate pluripotency,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Res
Prif Awduron: Buta, Christiane, David, Robert, Dressel, Ralf, Emgård, Mia, Fuchs, Christiane, Gross, Ulrike, Healy, Lyn, Hescheler, Jürgen, Kolar, Roman, Martin, Ulrich, Mikkers, Harald, Müller, Franz-Josef, Schneider, Rebekka K., Seiler, Andrea E.M., Spielmann, Horst, Weitzer, Georg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615844/
https://ncbi.nlm.nih.gov/pubmed/23611953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.03.001
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