Reconsidering pluripotency tests: Do we still need teratoma assays?

The induction of teratoma in mice by the transplantation of stem cells into extra-uterine sites has been used as a read-out for cellular pluripotency since the initial description of this phenomenon in 1954. Since then, the teratoma assay has remained the assay of choice to demonstrate pluripotency,...

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Udgivet i:Stem Cell Res
Main Authors: Buta, Christiane, David, Robert, Dressel, Ralf, Emgård, Mia, Fuchs, Christiane, Gross, Ulrike, Healy, Lyn, Hescheler, Jürgen, Kolar, Roman, Martin, Ulrich, Mikkers, Harald, Müller, Franz-Josef, Schneider, Rebekka K., Seiler, Andrea E.M., Spielmann, Horst, Weitzer, Georg
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615844/
https://ncbi.nlm.nih.gov/pubmed/23611953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.03.001
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