DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates

Ubiquitylation had been considered limited to protein lysine residues, but other substrates have recently emerged. Here, we show that DELTEX E3 ligases specifically target the 3′ hydroxyl of the adenosine diphosphate (ADP)–ribosyl moiety that can be linked to a protein, thus generating a hybrid ADP-...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Adv
Hlavní autoři: Zhu, Kang, Suskiewicz, Marcin J., Hloušek-Kasun, Andrea, Meudal, Hervé, Mikoč, Andreja, Aucagne, Vincent, Ahel, Dragana, Ahel, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2022
Témata:
Biomedicine and Life Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615817/
https://ncbi.nlm.nih.gov/pubmed/36197986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.add4253
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky