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Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
Homologous recombination (HR) is essential for error-free repair of DNA double-strand breaks, perturbed replication forks (RFs), and post-replicative single-stranded DNA (ssDNA) gaps. To initiate HR, the recombination mediator and tumor suppressor protein BRCA2 facilitates nucleation of RAD51 on ssD...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2023
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615647/ https://ncbi.nlm.nih.gov/pubmed/37499663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2023.06.031 |
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