Challenges in undertaking nonlinear Mendelian randomization

Mendelian randomization (MR) is a widely used method that exploits the unique properties of germline genetic variation to strengthen causal inference in relationships between exposures and outcomes. Nonlinear MR allows estimation of the shape of these relationships. In a previous paper, the authors...

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Bibliographic Details
Published in:Obesity (Silver Spring)
Main Authors: Wade, Kaitlin H., Hamilton, Fergus W., Carslake, David, Sattar, Naveed, Davey Smith, George, Timpson, Nicholas J.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2023
Subjects:
Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615556/
https://ncbi.nlm.nih.gov/pubmed/37845826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.23927
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