Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study

BACKGROUND: Earlier puberty is widely linked with future obesity and cardiometabolic disease. We examined whether age at puberty onset likely influences adiposity and cardiometabolic traits independent of childhood adiposity. METHODS AND FINDINGS: One-sample Mendelian randomisation (MR) analyses wer...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Bell, Joshua A., Carslake, David, Wade, Kaitlin H., Richmond, Rebecca C., Langdon, Ryan J., Vincent, Emma E., Holmes, Michael V., Timpson, Nicholas J., Davey Smith, George
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112630/
https://ncbi.nlm.nih.gov/pubmed/30153260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002641
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