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Single-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer entity characterized by a heterogeneous genetic landscape and an immunosuppressive tumor microenvironment. Recent advances in high-resolution single-cell sequencing and Spatial Transcriptomics technologies have enabled an in-depth cha...

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Detalhes bibliográficos
Publicado no:Nat Cancer
Main Authors: Bärthel, Stefanie, Falcomatà, Chiara, Rad, Roland, Theis, Fabian J., Saur, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615362/
https://ncbi.nlm.nih.gov/pubmed/36959420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-023-00526-x
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