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MTOR inhibitor-based combination therapies for pancreatic cancer
BACKGROUND: Although the mechanistic target of rapamycin (MTOR) kinase, included in the mTORC1 and mTORC2 signalling hubs, has been demonstrated to be active in a significant fraction of patients with pancreatic ductal adenocarcinoma (PDAC), the value of the kinase as a therapeutic target needs furt...
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| Veröffentlicht in: | Br J Cancer |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808033/ https://ncbi.nlm.nih.gov/pubmed/29384525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.421 |
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