Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir

Positron emission tomography (PET) imaging allows monitoring the progression of amyloid aggregation in the living brain. [(18)F]-Flortaucipir is the only approved PET tracer compound for the visualisation of tau aggregation. Here, we describe cryo-EM experiments on tau filaments in the presence and...

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Bibliografske podrobnosti
izdano v:J Mol Biol
Main Authors: Shi, Yang, Ghetti, Bernardino, Goedert, Michel, Scheres, Sjors H. W.
Format: Artigo
Jezik:Inglês
Izdano: 2023
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615338/
https://ncbi.nlm.nih.gov/pubmed/37330290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2023.168025
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