Pharmacological targeting netrin-1 inhibits EMT in cancer

Epithelial-to-mesenchymal transition (EMT) regulates tumour initiation, progression, metastasis and resistance to anti-cancer therapy(1–7). Although great progress has been made in understanding the role of EMT and its regulatory mechanisms in cancer, no therapeutic strategy to pharmacologically tar...

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Publicado no:Nature
Main Authors: Lengrand, Justine, Pastushenko, Ievgenia, Vanuytven, Sebastiaan, Song, Yura, Venet, David, Sarate, Rahul M., Bellina, Melanie, Moers, Virginie, Boinet, Alice, Sifrim, Alejandro, Rama, Nicolas, Ducarouge, Benjamin, Van Herck, Jens, Dubois, Christine, Scozzaro, Samuel, Lemaire, Sophie, Gieskes, Sarah, Bonni, Sophie, Collin, Amandine, Braissand, Nicolas, Allard, Justine, Zindy, Egor, Decaestecker, Christine, Sotiriou, Christos, Salmon, Isabelle, Mehlen, Patrick, Voet, Thierry, Bernet, Agnès, Blanpain, Cédric
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615210/
https://ncbi.nlm.nih.gov/pubmed/37532929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-023-06372-2
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