NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation

The non-genetic mechanisms required to sustain malignant tumor state are poorly understood. During the transition from benign tumors to malignant carcinoma, tumor cells need to repress differentiation and acquire invasive features. Using transcriptional profiling of cancer stem cells (CSC) from beni...

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Publicado no:Nat Cancer
Main Authors: Mauri, Federico, Schepkens, Corentin, Lapouge, Gaёlle, Drogat, Benjamin, Song, Yura, Pastushenko, Ievgenia, Rorive, Sandrine, Blondeau, Jeremy, Golstein, Sophie, Bareche, Yacine, Miglianico, Marie, Nkusi, Erwin, Rozzi, Milena, Moers, Virginie, Brisebarre, Audrey, Raphaёl, Maylis, Dubois, Christine, Allard, Justine, Durdu, Benoit, Ribeiro, Floriane, Sotiriou, Christos, Salmon, Isabelle, Vakili, Jalal, Blanpain, Cédric
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615150/
https://ncbi.nlm.nih.gov/pubmed/35122061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-021-00287-5
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