Mechanisms of stretch-mediated skin expansion at single-cell resolution

The ability of the skin to grow in response to stretching has been exploited in reconstructive surgery(1). Although the response of epidermal cells to stretching has been studied in vitro (2,3), it remains unclear how mechanical forces affect their behaviour in vivo. Here, we develop a mouse model i...

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Published in:Nature
Main Authors: Aragona, Mariaceleste, Sifrim, Alejandro, Malfait, Milan, Song, Yura, Van Herck, Jens, Dekoninck, Sophie, Gargouri, Souhir, Lapouge, Gaèlle, Swedlund, Benjamin, Dubois, Christine, Baatsen, Pieter, Vints, Katlijn, Han, Seungmin, Tissir, Fadel, Voet, Thierry, Simons, Benjamin D., Blanpain, Cédric
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116042/
https://ncbi.nlm.nih.gov/pubmed/32728211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2555-7
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