Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles

Poor understanding of intracellular delivery and targeting hinders development of nucleic acid-based therapeutics transported by nanoparticles. Utilizing a siRNA-targeting and small molecule profiling approach with advanced imaging and machine learning biological insights is generated into the mecha...

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Publicat a:Small Methods
Autors principals: Hunter, Morag Rose, Cui, Lili, Porebski, Benjamin Thomas, Pereira, Sara, Sonzini, Silvia, Odunze, Uchechukwu, Iyer, Preeti, Engkvist, Ola, Lloyd, Rebecca Louise, Peel, Samantha, Sabirsh, Alan, Ross-Thriepland, Douglas, Jones, Arwyn Tomos, Desai, Arpan Shailesh
Format: Artigo
Idioma:Inglês
Publicat: 2023
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615154/
https://ncbi.nlm.nih.gov/pubmed/37317010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smtd.202201695
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