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Using macropinocytosis for intracellular delivery of therapeutic nucleic acids to tumour cells
Nucleic acids are a rapidly emerging therapeutic modality with the potential to become the third major drug modality alongside antibodies and small molecules. Owing to the unfavourable physico-chemical characteristics of nucleic acids, such as large size and negative charge, intracellular delivery r...
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| Publicat a: | Philos Trans R Soc Lond B Biol Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6304741/ https://ncbi.nlm.nih.gov/pubmed/30967005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0156 |
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