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Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and antisense oligonucleotide (ASO), are powerful gene regulators, which have been demonstrated as promising drug candidates for therapeutic treatments. Nevertheless, poor cellular membrane permeability and serum stabilit...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cha, Wenzhang, Fan, Rengen, Miao, Yufeng, Zhou, Yong, Qin, Chenglin, Shan, Xiangxiang, Wan, Xinqiang, Li, Jinbo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154527/
https://ncbi.nlm.nih.gov/pubmed/28492505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22050782
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