Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and antisense oligonucleotide (ASO), are powerful gene regulators, which have been demonstrated as promising drug candidates for therapeutic treatments. Nevertheless, poor cellular membrane permeability and serum stabilit...

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Библиографические подробности
Опубликовано в: :Molecules
Главные авторы: Cha, Wenzhang, Fan, Rengen, Miao, Yufeng, Zhou, Yong, Qin, Chenglin, Shan, Xiangxiang, Wan, Xinqiang, Li, Jinbo
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2017
Предметы:
Review
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154527/
https://ncbi.nlm.nih.gov/pubmed/28492505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22050782
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