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Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and antisense oligonucleotide (ASO), are powerful gene regulators, which have been demonstrated as promising drug candidates for therapeutic treatments. Nevertheless, poor cellular membrane permeability and serum stabilit...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Cha, Wenzhang, Fan, Rengen, Miao, Yufeng, Zhou, Yong, Qin, Chenglin, Shan, Xiangxiang, Wan, Xinqiang, Li, Jinbo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154527/
https://ncbi.nlm.nih.gov/pubmed/28492505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22050782
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