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Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation

Oncogenic Ras has been shown to change the way cancer cells divide by increasing the forces generated during mitotic rounding. In this way, Ras(V12) enables cancer cells to divide across a wider range of mechanical environments than normal cells. Here, we identify a further role for oncogenic Ras-ER...

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Veröffentlicht in:Curr Biol
Hauptverfasser: Ganguli, Sushila, Wyatt, Tom, Nyga, Agata, Lawson, Rachel H., Meyer, Tim, Baum, Buzz, Matthews, Helen K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2023
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614879/
https://ncbi.nlm.nih.gov/pubmed/37343559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2023.05.061
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