LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

BACKGROUND: A poorly functioning tumor vasculature is pro-oncogenic and may impede the delivery of therapeutics. Normalizing the vasculature, therefore, may be beneficial. We previously reported that the secreted glycoprotein leucine-rich a-2-glycoprotein 1 (LRG1) contributes to pathogenic neovascul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Med
Egile Nagusiak: O’Connor, Marie N., Kallenberg, David M., Camilli, Carlotta, Pilotti, Camilla, Dritsoula, Athina, Jackstadt, Rene, Bowers, Chantelle E., Watson, H. Angharad, Alatsatianos, Markella, Ohme, Julia, Dowsett, Laura, George, Jestin, Blackburn, Jack W.D., Wang, Xiaomeng, Singhal, Mahak, Augustin, Hellmut G., Ager, Ann, Sansom, Owen J., Moss, Stephen E., Greenwood, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614757/
https://ncbi.nlm.nih.gov/pubmed/35590198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medj.2021.10.002
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