Investigations into Simplified Analogues of the Herbicidal Natural Product (+)‐Cornexistin

We report the design, synthesis and biological evaluation of simplified analogues of the herbicidal natural product (+)‐cornexistin. Guided by an X‐Ray co‐crystal structure of cornexistin bound to transketolase from Zea mays, we attempted to identify the key interactions that are necessary for corne...

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Détails bibliographiques
Publié dans:Chemistry
Auteurs principaux: Steinborn, Christian, Tancredi, Aldo, Habiger, Christoph, Diederich, Christina, Kramer, Jan, Reingruber, Anna M., Laber, Bernd, Freigang, Jörg, Lange, Gudrun, Schmutzler, Dirk, Machettira, Anu, Besong, Gilbert, Magauer, Thomas, Barber, David M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2023
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614749/
https://ncbi.nlm.nih.gov/pubmed/36807428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202300199
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