Crystal structures of the human IgD Fab reveal insights into C(H)1 domain diversity

Antibodies of the IgD isotype remain the least well characterised of the mammalian immunoglobulin isotypes. Here we report three-dimensional structures for the Fab region of IgD, based on four different crystal structures, at resolutions of 1.45-2.75 Å. These IgD Fab crystals provide the first high-...

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Publicat a:Mol Immunol
Autors principals: Davies, Anna M., Beavil, Rebecca L., Barbolov, Momchil, Sandhar, Balraj S., Gould, Hannah J., Beavil, Andrew J., Sutton, Brian J., McDonnell, James M.
Format: Artigo
Idioma:Inglês
Publicat: 2023
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614686/
https://ncbi.nlm.nih.gov/pubmed/37267832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2023.05.006
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