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Total Syntheses of (+)-Waixenicin A, (+)-9-Deacetoxy-14,15-deepoxyxeniculin, and (−)-Xeniafaraunol A
[Image: see text] The first asymmetric total synthesis of the Xenia diterpenoid waixenicin A, a potent and highly selective TRPM7 inhibitor, is reported. The characteristic trans-fused oxabicyclo[7.4.0]tridecane ring system was constructed via a diastereoselective conjugate addition/trapping sequenc...
Tallennettuna:
| Julkaisussa: | J Am Chem Soc |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Chemical Society
2023
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614607/ https://ncbi.nlm.nih.gov/pubmed/37192136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.3c03366 |
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