Evolutionary characterisation of lung adenocarcinoma morphology in TRACERx

Lung adenocarcinomas (LUADs) display a broad histological spectrum from low-grade lepidic tumours through to mid-grade acinar and papillary and high-grade solid, cribriform and micropapillary tumours. Little is known as to how morphology reflects tumour evolutionary history and disease progression....

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Udgivet i:Nat Med
Main Authors: Karasaki, Takahiro, Moore, David A., Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Magno, Neil, Ward, Sophia, Al Bakir, Maise, Watkins, Thomas B.K., Grigoriadis, Kristiana, Huebner, Ariana, Hill, Mark S., Frankell, Alexander M., Abbosh, Christopher, Gimeno-Valiente, Francisco, Saghafinia, Sadegh, Kanu, Nnennaya, Dietzen, Michelle, Pich, Oriol, Lim, Emilia, Martinez-Ruiz, Carlos, Black, James R.M., Puttick, Clare, Biswas, Dhruva, Campbell, Brittany B., Lee, Claudia, Colliver, Emma, Enfield, Katey S.S., Hessey, Sonya, Hiley, Crispin T., Zaccaria, Simone, Litchfield, Kevin, Birkbak, Nicolai J., Cadieux, Elizabeth Larose, Demeulemeester, Jonas, Van Loo, Peter, Adusumilli, Prasad S., Tan, Kay See, Cheema, Waseem, Sanchez-Vega, Francisco, Jones, David R., Rekhtman, Natasha, Travis, William D., Hackshaw, Allan, Marafioti, Teresa, Salgado, Roberto, Le Quesne, John, Nicholson, Andrew G., McGranahan, Nicholas, Swanton, Charles, Jamal-Hanjani, Mariam
Format: Artigo
Sprog:Inglês
Udgivet: 2023
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614478/
https://ncbi.nlm.nih.gov/pubmed/37045996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-023-02230-w
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