Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization

Crossing the blood-brain barrier is a crucial, rate-limiting step of brain metastasis. Understanding of the mechanisms of cancer cell extravasation from brain microcapillaries is limited as the underlying cellular and molecular processes cannot be adequately investigated using in vitro models and en...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Karreman, Matthia A., Bauer, Alexander T., Solecki, Gergely, Berghoff, Anna S., Mayer, Chanté D., Frey, Katharina, Hebach, Nils, Feinauer, Manuel J., Schieber, Nicole L., Tehranian, Cedric, Mercier, Luc, Singhal, Mahak, Venkataramani, Varun, Schubert, Marc C., Hinze, Daniel, Hölzel, Michael, Helfrich, Iris, Schadendorf, Dirk, Schneider, Stefan W., Westphal, Dana, Augustin, Hellmut G., Goetz, Jacky G., Schwab, Yannick, Wick, Wolfgang, Winkler, Frank
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2023
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614438/
https://ncbi.nlm.nih.gov/pubmed/36652557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-22-3964
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