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Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization

Crossing the blood-brain barrier is a crucial, rate-limiting step of brain metastasis. Understanding of the mechanisms of cancer cell extravasation from brain microcapillaries is limited as the underlying cellular and molecular processes cannot be adequately investigated using in vitro models and en...

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出版年:Cancer Res
主要な著者: Karreman, Matthia A., Bauer, Alexander T., Solecki, Gergely, Berghoff, Anna S., Mayer, Chanté D., Frey, Katharina, Hebach, Nils, Feinauer, Manuel J., Schieber, Nicole L., Tehranian, Cedric, Mercier, Luc, Singhal, Mahak, Venkataramani, Varun, Schubert, Marc C., Hinze, Daniel, Hölzel, Michael, Helfrich, Iris, Schadendorf, Dirk, Schneider, Stefan W., Westphal, Dana, Augustin, Hellmut G., Goetz, Jacky G., Schwab, Yannick, Wick, Wolfgang, Winkler, Frank
フォーマット: Artigo
言語:Inglês
出版事項: 2023
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614438/
https://ncbi.nlm.nih.gov/pubmed/36652557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-22-3964
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