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Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

DNA damage response (DDR) during interphase involves active signaling and repair to ensure genomic stability. However, how mitotic cells respond to DNA damage remains poorly understood. Supported by correlative live-/fixed-cell microscopy, it was found that mitotic cells exposed to several cancer ch...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Novais-Cruz, Marco, Pombinho, António, Sousa, Mafalda, Maia, André F., Maiato, Helder, Ferrás, Cristina
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2023
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614429/
https://ncbi.nlm.nih.gov/pubmed/36989031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E22-11-0518
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