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Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

DNA damage response (DDR) during interphase involves active signaling and repair to ensure genomic stability. However, how mitotic cells respond to DNA damage remains poorly understood. Supported by correlative live-/fixed-cell microscopy, it was found that mitotic cells exposed to several cancer ch...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Novais-Cruz, Marco, Pombinho, António, Sousa, Mafalda, Maia, André F., Maiato, Helder, Ferrás, Cristina
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2023
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614429/
https://ncbi.nlm.nih.gov/pubmed/36989031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E22-11-0518
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