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Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

DNA damage response (DDR) during interphase involves active signaling and repair to ensure genomic stability. However, how mitotic cells respond to DNA damage remains poorly understood. Supported by correlative live-/fixed-cell microscopy, it was found that mitotic cells exposed to several cancer ch...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Novais-Cruz, Marco, Pombinho, António, Sousa, Mafalda, Maia, André F., Maiato, Helder, Ferrás, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2023
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614429/
https://ncbi.nlm.nih.gov/pubmed/36989031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E22-11-0518
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