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Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry

The potential importance of the methylation cycle during embryonic development necessitates the establishment of methodology to detect alterations in the relative abundance of SAM and SAH in an embryonic experimental system. We have developed a precise and sensitive method for measurement of SAM and...

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Pubblicato in:J Chromatogr B Analyt Technol Biomed Life Sci
Autori principali: Burren, Katie, Mills, Kevin, Copp, Andrew J., Greene, Nicholas D.E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614419/
https://ncbi.nlm.nih.gov/pubmed/16890031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2006.07.012
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