Simultaneous Phenotyping and Quantitation of α-1-Antitrypsin by liquid chromatography-tandem mass spectrometry

BACKGROUND: α-1-antitrypsin (A1AT) deficiency results from a genetic disorder at two common loci. Diagnosis requires quantitation of A1AT and subsequent identification of the specific variant. The current algorithm of laboratory testing for the diagnosis of A1AT deficiency uses a combination of quan...

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Main Authors: Chen, Yuhong, Snyder, Melissa R., Zhu, Yi, Tostrud, Linda J., Benson, Linda M., Katzmann, Jerry A., Bergen, H. Robert
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275912/
https://ncbi.nlm.nih.gov/pubmed/21636698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2011.163006
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