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Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry

The potential importance of the methylation cycle during embryonic development necessitates the establishment of methodology to detect alterations in the relative abundance of SAM and SAH in an embryonic experimental system. We have developed a precise and sensitive method for measurement of SAM and...

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Publicat a:J Chromatogr B Analyt Technol Biomed Life Sci
Autors principals: Burren, Katie, Mills, Kevin, Copp, Andrew J., Greene, Nicholas D.E.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614419/
https://ncbi.nlm.nih.gov/pubmed/16890031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2006.07.012
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