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Future prospects for human genetics and genomics in drug discovery

Evidence from human genetics supporting the therapeutic hypothesis increases the likelihood that a drug will succeed in clinical trials. Rare and common disease genetics yield a wide array of alleles with a range of effect sizes that can proxy for the effect of a drug in disease. Recent advances in...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Ghoussaini, Maya, Nelson, Matthew R., Dunham, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614359/
https://ncbi.nlm.nih.gov/pubmed/36963162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2023.102568
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