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HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly
HIV-1 Gag metamorphoses inside each virion from an immature lattice that forms during viral production to a mature capsid that drives infection. Here we show that the immature lattice is required to concentrate the cellular metabolite inositol hexakisphosphate (IP6) into virions to catalyse mature c...
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| Pubblicato in: | Nat Struct Mol Biol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2023
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614341/ https://ncbi.nlm.nih.gov/pubmed/36624347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-022-00887-4 |
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