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HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly
HIV-1 Gag metamorphoses inside each virion from an immature lattice that forms during viral production to a mature capsid that drives infection. Here we show that the immature lattice is required to concentrate the cellular metabolite inositol hexakisphosphate (IP6) into virions to catalyse mature c...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Struct Mol Biol |
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| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2023
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614341/ https://ncbi.nlm.nih.gov/pubmed/36624347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-022-00887-4 |
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