IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network

The NLRP3 inflammasome plays a central role in antimicrobial defense as well as in the context of sterile inflammatory conditions. NLRP3 activity is governed by two independent signals: the first signal primes NLRP3, rendering it responsive to the second signal, which then triggers inflammasome form...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Schmacke, Niklas A., O’Duill, Fionan, Gaidt, Moritz M., Szymanska, Inga, Kamper, Julia M., Schmid-Burgk, Jonathan L., Mädler, Sophia C., Mackens-Kiani, Timur, Kozaki, Tatsuya, Chauhan, Dhruv, Nagl, Dennis, Stafford, Che A., Harz, Hartmann, Fröhlich, Adrian L., Pinci, Francesca, Ginhoux, Florent, Beckmann, Roland, Mann, Matthias, Leonhardt, Heinrich, Hornung, Veit
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614333/
https://ncbi.nlm.nih.gov/pubmed/36384135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2022.10.021
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados