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OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines
The application of designer nucleases allows the induction of DNA double-strand breaks (DSBs) at user-defined genomic loci. Due to imperfect DNA repair mechanisms, DSBs can lead to alterations in the genomic architecture, such as the disruption of the reading frame of a critical exon. This can be ex...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199374/ https://ncbi.nlm.nih.gov/pubmed/25186908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.176701.114 |
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