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Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

The innate immune defence of multicellular organisms against microbial pathogens requires cellular collaboration. Information exchange allowing immune cells to collaborate is generally attributed to soluble protein factors secreted by pathogen-sensing cells. Cytokines, such as type I interferons (IF...

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Detalhes bibliográficos
Main Authors: Ablasser, Andrea, Schmid-Burgk, Jonathan L., Hemmerling, Inga, Horvath, Gabor L., Schmidt, Tobias, Latz, Eicke, Hornung, Veit
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142317/
https://ncbi.nlm.nih.gov/pubmed/24077100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12640
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