Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation in Asian breast cancer patients

PURPOSE: With the development of PARP inhibitors for treatment of cancer patients with an altered BRCA1 or BRCA2 gene, there is an urgent need to ensure that there are appropriate strategies for identifying mutation carriers whilst balancing the increased demand for and cost of cancer genetics servi...

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Pubblicato in:J Clin Oncol
Autori principali: Ang, Boon Hong, Ho, Weang Kee, Wijaya, Eldarina, Kwan, Pui Yoke, Ng, Pei Sze, Yoon, Sook Yee, Hasan, Siti Norhidayu, Lim, Joanna M. C., Hassan, Tiara, Tai, Mei-Chee, Allen, Jamie, Lee, Andrew, Taib, Nur Aishah Mohd, Yip, Cheng Har, Hartman, Mikael, Lim, Swee Ho, Tan, Ern Yu, Tan, Benita K. T., Tan, Su-Ming, Tan, Veronique K. M., Ho, Peh Joo, Khng, Alexis J., Dunning, Alison M., Li, Jingmei, Easton, Douglas F., Antoniou, Antonis C., Teo, Soo Hwang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2022
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614269/
https://ncbi.nlm.nih.gov/pubmed/35143328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.21.01647
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