Gaucher disease protects against tuberculosis

Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease, characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in macrophages. Gaucher and other lysosomal diseases occur with high frequency in Ashkenazi Jews. It has been proposed that the underly...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Fan, Jingwen, Hale, Victoria L., Lelieveld, Lindsey T., Whitworth, Laura J., Busch-Nentwich, Elisabeth M., Troll, Mark, Edelstein, Paul H., Cox, Timothy M., Roca, Francisco J., Aerts, Johannes M. F. G., Ramakrishnan, Lalita
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2023
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614233/
https://ncbi.nlm.nih.gov/pubmed/36745788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2217673120
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items