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Stereoselective Syntheses of Masked β-Amino Acid Containing Phthalides
We herein report a protocol for the asymmetric aldol-initiated cascade addition of isoxazolidin-5-ones to ortho-cyanobenzaldehydes by using Takemoto’s bifunctional organocatalyst. This approach allows for the synthesis of various novel β(2,2)-amino acid-phthalide conjugates with good enantio- and di...
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| Publicado no: | Helv Chim Acta |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614226/ https://ncbi.nlm.nih.gov/pubmed/36845268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hlca.202200110 |
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